For our kitchen cabinets, I wanted movable shelves, and using the Domino to cut shelf pin holes seemed like a natural idea. I cut two lengths of plywood, and attached a strip on the end that let me set the plywood up against the side to give me 90°. Both pieces were the same thickness, the spacing I wanted for my shelves.
Then I just clamped them to the board, cut my pins, moved one guide past the other, and repeated the process. Poof, instant shelf pins!
This was inspired by http://festoolownersgroup.com/index.php?topic=2415.0